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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20939 | Bimatoprost acid | 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α | GPR |
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP... | |||
T30452 | Bimatoprost isopropyl ester | 17-phenyl trinor PGF2α-iPr,17-phenyl trinor PGF2α isopropyl ester | |
Bimatoprost isopropyl ester is an F-series prostaglandin analog, which has been approved as a hypotensive drug. | |||
T37940 | 17-phenyl trinor Prostaglandin F2α cyclopropyl amide | 17-phenyl trinor Prostaglandin F2α cyclopropyl amide | |
17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide. There are no published reports on the biological activity of 17-phe... | |||
T35944 | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | |
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidati... | |||
T37941 | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide | 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide | |
Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that... | |||
T37944 | 17-phenyl trinor Prostaglandin F2α methyl amide | 17-phenyl trinor Prostaglandin F2α methyl amide | |
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The et... | |||
T37946 | 17-trifluoromethylphenyl trinor Prostaglandin F2α | 17-trifluoromethylphenyl trinor Prostaglandin F2α | |
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most pote... | |||
T37930 | 15(R)-17-phenyl trinor Prostaglandin F2α | 15(R)-17-phenyl trinor Prostaglandin F2α | |
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl tr... | |||
T36908 | Bimatoprost grenod | 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α | |
Bimatoprost grenod(15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α.1It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically adm... | |||
T37945 | Bimatoprost methyl ester | 17-phenyl trinor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17... | |||
T37947 | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-triflu... | |||
T37938 | 17-phenoxy trinor Prostaglandin F2α ethyl amide | 17-phenoxy trinor Prostaglandin F2α ethyl amide | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2α and 16-phenoxy tetranor PGF2α are metabolically stable anal... | |||
T37943 | 17-phenyl trinor Prostaglandin F2α isopropyl ester | 17-phenyl trinor Prostaglandin F2α isopropyl ester | |
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod... | |||
T37777 | 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide | 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2... | |||
T37948 | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | |
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relat... | |||
T37934 | 15-keto-17-phenyl trinor Prostaglandin F2α | 15-keto-17-phenyl trinor Prostaglandin F2α | |
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trin... | |||
T37939 | N-Desethyl Bimatoprost | 17-phenyl trinor Prostaglandin F2α amide | |
N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. P... |